Carnitine is a naturally occurring substance, which is essential for fatty acid oxidation and energy production. Without it, long-chain fatty acids cannot cross from cellular cytoplasma into the mitochondria and out again, resulting in loss of energy and toxic accumulations of free fatty acids. Ninety-five percent of the body' carnitine is found in cardiac and skeletal tissue; these muscles rely upon fatty acid oxidation for most of their energy.

INDICATIONS

Dietary supplementation of L-Carnitine for individuals who may benefit from supplementation of this essential nutrient. Renal dialysis patients and individuals with immune system deficiencies may benefit from L-Carnitine supplementation.

ADVERSE REACTIONS

None reported.

SUGGESTED USE

As a dietary supplement: Adults, one gram daily or as directed by physician, registered dietician or nutritionist. Children, as directed by physician.

HOW SUPPLIED

250mg tablets in bottles of 90 NDC 54022-2100-1

500mg scored caplets in bottles of 30 NDC 54022-2120-1

500mg chewable wafers in bottles of 30 NDC 54022-2700-1

500mg capsules in bottles of 30 NDC 54022-2800-1

REFERENCES

1) Effects of L-Carnitine Supplementation on Muscular Symptoms in Hemodialyzed Patients. Y. Saskurauchi, Y. Matsumoto, T. Shinzato, I. Takai, Y. Nakamura, M. Sato, S. Nakai, M. Miwa, H. Morita, T. Miwa, I. Amano, K. Maeda, American Journal of Kidney Diseases, 32(2)258-264, August 1998

2) Anemia and Carnitine Supplementation in Hemodialyzed Patients. Kletzmajr, J., et al., Kidney International, 55(Suppl 69):S93-S106, March 1999

3) Carnitine and its Derivatives in Cardiovascular Disease. Arsenian, M.A., Progress in Cardiovascular Diseases, 40(3):265-286, Nov.-Dec. 1997