Coenzyme Q 10 (CoQ 10 ) is an essential nutrient that is a cofactor in the mitochondrial electron transport chain, the biochemical pathway in cellular respiration from which ATP and metabolic energy are derived. Since nearly all cellular functions are dependent on energy, CoQ 10 is essential for the health of all human tissues and organs. The involvement of CoQ 10 as a redox carrier of the respiratory chain is well established on the basis of both reconstitution studies and kinetic evidence.
In addition to CoQ 10 's vital role in cellular energy production, it also functions as a powerful, highly effective antioxidant. These functions of CoQ 10 support normal heart function. Studies show that CoQ 10 also enhances vitamin E's ability to destroy free radicals.
As a dietary supplement: Adults, 60mg-200mg daily or as directed by physician or registered dietician. Children, as directed by physician.
None reported.
Bottles of 30, 60, 500 and 1000.
200mg with 400 I.U. Vitamin E chewable wafers, NDC 54022-2091, 100mg with 300 I.U. Vitamin E chewable wafers, NDC 54022-2090, 60mg chewable wafers, NDC 54022-2085, 200mg tablets, NDC 54022-8002, 60mg tablets, NDC 54022-2081, 25mg tablets, NDC 54022-2055, 60mg Liposphere softgels 54022-2075
1) Coenzyme Q 10 Administration Increases Brain Mitochondrial Concentrations and Exerts Neuroprotective Effects. Matthews, R.T., Beal, M.F., et al. Proceedings of the National Academy of Sciences of the United States of America , 95(15):8892-7, July 21, 1998
2) Overview of the Use of CoQ 10 in Cardiovascular Disease. Langsjoen, P., The First Conference of the International Co-Enzyme Q 10 Association , Boston, MA, May 21-24, 1998 (reprint available)
3) Plasma Coenzyme Q 10 Concentrations in Breast Cancer: Prognosis and Therapeutic Consequences. P. Jolliet, et al., International Journal of Clinical Pharmacology and Therapeutics , 36(9):506-9, 1998
4) Absorption, Tolerability, and Effects on Mitochondrial Activity of Oral Coenzyme Q10 in Parkinsonian Patients. Shultz C.W., et al. Neurology , 50:793-795, March 1998
5) Introduction to Coenzyme Q 10 . Langsjoen, Peter H., M.D., F.A.C.C., Tyler, TX 75701, 1996